18 months starting September 2020

Post-doctoral position in cell biology/cancer photobiology


Photothermal therapy (PTT) is one of the most efficient therapies that can induce necrosis of specific malignant lesions with minimal invasiveness and side effects compared with other therapeutic modalities.

In this context, applications are open for a postdoctoral fellowship position funded by the “FireLight” projet-FEDER – Photoactive molecules and nanoparticles.

The position will be based at L2CM (http://www.l2cm.univ-lorraine.fr/l2cm/), CRAN (http://www.cran.univ-lorraine.fr/) and ICL (http://www.icl-lorraine.fr/) laboratories in Nancy (France).

The research program will focus on the development of indocyanine green (ICG) loaded Solid Lipid Nanoparticles (SLN) and on the characterization of photophysical (size and charges measurements, spectral characterization, thermal effect) and photobiological properties (uptake, intracellular fluorescence and localization, therapeutic efficiency). The biological model used will be 2D and 3D cell cultures and animal models.

Selection process: Interested candidates should send a CV, a scientific track record, a motivation letter and two recommendation letters to:

Dr. Henri-Pierre Lassalle / Prof. Andreea Pasc

Contact: henri-pierre.lassalle@univ-lorraine.fr; andreea.pasc@univ-lorraine.fr

Skills/Qualifications: Candidates for this postdoctoral fellowship must hold a PhD degree in cell biology, good knowledge in photobiology will be required, as well as experience in animal experiments (the authorization to experiment on animals will be highly appreciated). Creativity, autonomy and strong reliability are highly required. All applicants must be able to communicate fluently in French and/or English (speaking and writing). The position is available for a period of 18 months, starting from September 2020.

Keywords: Cancer, Nanoparticle, Photothermal therapy (PTT), NIR fluorescence, Indocyanine green, Photodiagnosis.

Prof. Andreea Pasc - Contacter
L2CM - Laboratoire Lorraine de Chimie Moléculaire
CRAN - Centre de Recherche en Automatique de Nancy
ICL - Institut de Cancérologie de Lorraine
Université de Lorraine

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more details in the job offer desciption (file attached)