IJB axis M3V project, 2018
New C-glyco”RGD” derivatives: synthesis and molecular modeling
This project consists of the synthesis of C-glycoRGD derivatives (RGD peptides coupled to a C-glycoside), then in vitro evaluation of their specificity towards the integrins aIIbb3 and aVb3 (collaboration with the DCAC laboratory). Molecular modeling studies conducted by the LPCT laboratory will rationalize the binding of C-glycoRGD to these integrins.
L2CM laboratory: Nadia Pellegrini-Moïse et Sandrine Lamandé-Langle
LPCT laboratory: François Dehez et Antonio Monari